Egas Moniz

Creator of Cerebral Angiography and pioneer of Psychosurgery

Egas Moniz was a Portuguese neurologist who invented Cerebral Angiography and pré-frontal Leucotomy, for wich he won a Nobel Prize in 1949.

The cerebral angiography
  • Moniz developed the cerebral angiography, a medical imaging technique that allows visualization of blood vessels in the brain. This innovation significantly advanced the field of neurology by providing a non-invasive way to study the blood supply to the brain and diagnose brain tumours that would't be diagnosible without the technique.

The Prefrontal Leucotomy
  • Although controversial and now largely discredited, Moniz pioneered the development of prefrontal lobotomy as a treatment for certain mental illnesses. This procedure involved the surgical disconnection of the prefrontal cortex from the rest of the brain and was initially hailed as a breakthrough in psychiatry. However, it fell out of favour due to ethical concerns and the development of more effective and less invasive psychiatric treatments.  

Nobel Prize in Physiology or Medicine (1949)
  • Egas Moniz was awarded the Nobel Prize in Physiology or Medicine in 1949, along with Walter Rudolf Hess, for his discovery of the therapeutic value of prefrontal leucotomy in certain psychoses. He was nominated five (5) times for Nobel Prize before he won the award.

Egas Moniz's contributions to neurology and medicine, particularly the development of cerebral angiography, have had a lasting impact on the understanding and treatment of neurological disorders. However, it's important to note that his work on prefrontal leucotomy (also known as lobotomy) is viewed with more controversy today due to ethical considerations and the evolution of psychiatric treatments.




Sigmund Freud

Founder of Psychoanalysis

Moniz was deeply influenced by Freud's work, practicing psychoanalysis himself and organising many seminars on this topic as a university teacher.

Albert Pitres

Neurologist and professor

Like Freud, Pitres was a Charcot student in Paris. Moniz went to Bordeaux to study with him, considering him one of the main references in clinical neurology.

Emmanuel Régis

Psychiatrist and professor

Moniz studied with Régis, considering him one of the greatest specialists at the time in psychiatry and mental illness. Régis became known to be one of the most important semiologists in France in the early 20th century.

Almeida Lima

Neurosurgeon and Moniz co-worker

Although he was younger than Moniz and also his student, Lima had a great influence on his master, not only helping him to perform surgical procedures like angiography and prefrontal leucotomy (due to Moniz's arthritis), but also being his scientific partner and confident.

Antunes, J. L. (2011). Egas Moniz: uma biografia. Gradiva Publicações. 

Curtis, J. B. (1951). Cerebral angiography. Journal of British Surgery, 38(151), 295-331. 

De Almeida Lima, P. M. (1950). Cerebral angiography. Oxford University Press. 

Lima, A. (1948). ORIGINALES: Angiografía cerebrla y leucotomia prefrontal. In Anales de medicina y cirugía (pp. 16-26). 

Lowis, G. W., & Minagar, A. (2003). The neglected research of Egas Moniz of internal carotid artery (ICA) occlusion. Journal of the History of the Neurosciences, 12(3), 286-291. 

Moniz, E. (1922). A vida sexual: fisiologia e patologia

Moniz, E. (1931). Diagnostic des tumeurs cérébrales et épreuve de l'encéphalographie artérielle. In Diagnostic des tumeurs cérébrales et épreuve de l'encéphalographie artérielle (pp. 221-221). 

Moniz, E. (1933). Cerebral angiography: Its application in clinical practice and physiology. The Lancet, 222(5751), 1144-1147. 

Moniz, E. (1936). Tentatives opératoires dans le traitement de certaines psychoses. In Tentatives opératoires dans le traitement de certaines psychoses (pp. 248-248). 

Moniz, E. (1937). Prefrontal leucotomy in the treatment of mental disorders. American Journal of Psychiatry, 93(6), 1379-1385. 

Moniz, E. (1949). Confidências de um investigador científico. Edições Ática. Moniz, E., Lima, A., & de Lacerda, R. (1937). Hemiplegies par thrombose de la carotide interne. Presse méd, 45(June), 977-980.

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